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ECCO 2019: IBD cancer and serious infections in Europe (I-CARE study)

Prospective studies specifically assessing the effectiveness and safety profile of current therapeutic strategies based on a wider use of biologics in inflammatory bowel disease (IBD) are lacking. The overall objectives of I-CARE -a European prospective observationalstudy -are to assess:

1) the long-term safety profile (malignancy, infections) of immunomodulators (IMM), biologics (anti-TNF and vedolizumab) alone or in combination with an Iimmunomodulator

2) the potential for disease modification of biologics

3) the benefit-risk ratio of current therapeutic strategies

4) health economics of IBD care

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